Additive Manufacturing Approaches for Hydroxyapatite‐Reinforced Composites

Authors: Mario Milazzo, Nicola Contessi Negrini, Stefania Scialla, Benedetto Marelli, Silvia Farè, Serena Danti, Markus J. Buehler*

Keywords: bioinks, bioinspired, composites, hierarchical, hydroxyapatite, materiomics, tissue engineering.

Limitations: An interconnected porosity represents a necessary condition for vascularization, but few studies have evaluated the capability of the constructs to allow the flows of nutrients needed to avoid the necrosis of the tissues and the embodiment in the host site.

Benefits: These composites are used mainly as tools to promote/replace cartilaginous and bone structures due to their chemical similarities to the native tissues.

Practical implications: growth and development of biomatrix.

Originality/value: have found a new material for production of biological scaffolds.

Full reference: : MILAZZO M., CONTESSI NEGRINI N., SCIALLA S., MARELLI B., FARÈ S., DANTI S., BUEHLER M. J., Additive Manufacturing Approaches for Hydroxyapatite‐Reinforced Composites - www.afm-journal.de.

Link: https://doi.org/10.1002/adfm.201903055; DOI: 10.1002/adfm.201903055; https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201903055.

*Dr. M. Milazzo, Prof. S. Danti The BioRobotics Institute Scuola Superiore Sant’Anna Viale Rinaldo Piaggio 34, 56025 Pontedera (PI), Italy Dr. M. Milazzo, Dr. N. Contessi Negrini, Prof. B. Marelli, Prof. S. Danti, Prof. M. J. Buehler Department of Civil and Environmental Engineering at Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139, USA E-mail: mbuehler@mit.edu Dr. N. Contessi Negrini, Prof. S. Fare Department of Chemistry Materials and Chemical Engineering “G. Natta” Politecnico di Milano Piazza Leonardo da Vinci 32, 20133 Milan, Italy Dr. S. Scialla Institute of Nanotechnology (NANOTEC) National Research Council Via per Monteroni c/o Campus Ecotekne 73100, Lecce, Italy Prof. S. Danti Department of Civil and Industrial Engineering University of Pisa Largo L. Lazzarino 2, 56122 Pisa, Italy